The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Jan. 17, 2007
Karl Schoenafinger, Alzenau, DE;
Gerhard Jaehne, Frankfurt, DE;
Elisabeth Defossa, Idstein, DE;
Lothar Schwink, Stadtallendorf, DE;
Holger Wagner, Biberach/Mettenberg, DE;
Christian Buning, Bonn, DE;
Georg Tschank, Essenheim, DE;
Ulrich Werner, Miehlen, DE;
Karl Schoenafinger, Alzenau, DE;
Gerhard Jaehne, Frankfurt, DE;
Elisabeth Defossa, Idstein, DE;
Lothar Schwink, Stadtallendorf, DE;
Holger Wagner, Biberach/Mettenberg, DE;
Christian Buning, Bonn, DE;
Georg Tschank, Essenheim, DE;
Ulrich Werner, Miehlen, DE;
sanofi-aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
Compounds for the treatment of elevated blood glucose levels and the physiological and metabolic disorders arising therefrom are disclosed and comprise novel substituted bicyclic 8-pyrrolidinoxanthines and their derivatives of formula I: wherein the various R groups are hereinafter defined. The present invention also comprises pharmaceutical compositions comprising them as well as processes for the preparation of these compounds. Particular blood glucose disorders treatable thereby include type-2 diabetes, insulin resistance, hyperglycemia, arteriosclerotic diseases and the like.