The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Feb. 05, 2003
Daniel Spinks, Newhouse-Scotland, GB;
Richard E. Armer, Newhouse-Scotland, GB;
David J. Miller, Newhouse-Scotland, GB;
Zoran Rankovic, Newhouse-Scotland, GB;
Gayle Spinks, Newhouse-Scotland, GB;
Jordi Mestres, Newhouse-Scotland, GB;
David Robert Jaap, Oss, NL;
Daniel Spinks, Newhouse-Scotland, GB;
Richard E. Armer, Newhouse-Scotland, GB;
David J. Miller, Newhouse-Scotland, GB;
Zoran Rankovic, Newhouse-Scotland, GB;
Gayle Spinks, Newhouse-Scotland, GB;
Jordi Mestres, Newhouse-Scotland, GB;
David Robert Jaap, Oss, NL;
N.V. Organon, Oss, NL;
Abstract
The present invention relates to 1-arylsulfonyl-3 substituted indole or indoline derivatives having the general formula (I) (I) wherein the dotted line represents an optional bond; n is 0 or 1; m is 0-5 and Ar, R6-R11 are defined in the description. The invention further relates to pharmaceutical compositions comprising said derivatives, and to the use of these 1-arylsulfonyl-3-substituted indole or indoline derivatives in the treatment of central nervous disorders such as psychosis, schizophrenia, manic depressions, depressions, neurological disorders, cognitive enhancement, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's disease.