The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2010
Filed:
Jan. 17, 2008
Manlio Palumbo, Padua, IT;
Barbara Gatto, Padua, IT;
Rodolfo Pescador, Milan, IT;
Roberto Porta, Cernobbio, IT;
Laura Iris Ferro, Milan, IT;
Manlio Palumbo, Padua, IT;
Barbara Gatto, Padua, IT;
Rodolfo Pescador, Milan, IT;
Roberto Porta, Cernobbio, IT;
Laura Iris Ferro, Milan, IT;
Gentium SpA, Villa Guardia (CO), IT;
Abstract
The present research is directed to the identification of non-peptidic inhibitors of cathepsin G characterised by high levels of selectivity and which can be efficaciously used in the treatment and prophylaxis of inflammatory occurrences and procoagulant conditions. The cathepsin G-inhibiting aptamers according to the invention consist of linear DNA or polynucleotide sequences having a chain length of at least 60 nucleotides and being substantially not subjected to undergo efficient base pairing.