The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2010

Filed:

Feb. 09, 2007
Applicants:

Toru Yamazaki, Tokyo, JP;

Shigeyuki Kikumoto, Tokyo, JP;

Masahiro Ono, Kanagawa, JP;

Atsushi Saitou, Chiba, JP;

Haruka Takahashi, Tokyo, JP;

Sei Kumakura, Saitama, JP;

Kunitaka Hirose, Tokyo, JP;

Mikiro Yanaka, Chiba, JP;

Yoshiyuki Takemura, Tokyo, JP;

Shigeru Suzuki, Tokyo, JP;

Ryo Matsui, Tokyo, JP;

Inventors:

Toru Yamazaki, Tokyo, JP;

Shigeyuki Kikumoto, Tokyo, JP;

Masahiro Ono, Kanagawa, JP;

Atsushi Saitou, Chiba, JP;

Haruka Takahashi, Tokyo, JP;

Sei Kumakura, Saitama, JP;

Kunitaka Hirose, Tokyo, JP;

Mikiro Yanaka, Chiba, JP;

Yoshiyuki Takemura, Tokyo, JP;

Shigeru Suzuki, Tokyo, JP;

Ryo Matsui, Tokyo, JP;

Assignee:

Kureha Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/02 (2006.01); A01N 43/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C(═O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl.


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