The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2010
Filed:
Sep. 22, 2006
Pietro Ciceri, San Diego, CA (US);
Patrick Parvis Zarrinkar, San Diego, CA (US);
Daniel Kelly Treiber, San Diego, CA (US);
David J. Lockhart, Del Mar, CA (US);
Pietro Ciceri, San Diego, CA (US);
Patrick Parvis Zarrinkar, San Diego, CA (US);
Daniel Kelly Treiber, San Diego, CA (US);
David J. Lockhart, Del Mar, CA (US);
Ambit Biosciences Corporation, San Diego, CA (US);
Abstract
The present invention provides an advance in phage display technology by permitting the uncoupling of the propagation of phages containing inserted sequences encoding heterologous polypeptides from the expression of said polypeptides. The invention provides phage constructs and methods for their use to permit phage coat protein expression, and thus phage propagation, in the absence of display of heterologous polypeptides, which may be expressed as a fusion with said coat protein in a regulated manner.