The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2010
Filed:
Jan. 18, 2007
Markus Schweitzer, Frankfurt am Main, DE;
Norbert Windhab, Hofheim am Taunus, DE;
John R. Havens, Arlington, MA (US);
Thomas J. Onofrey, Poway, CA (US);
Charles Greef, Boulder, CO (US);
Daguang Wang, Vista, CA (US);
Markus Schweitzer, Frankfurt am Main, DE;
Norbert Windhab, Hofheim am Taunus, DE;
John R. Havens, Arlington, MA (US);
Thomas J. Onofrey, Poway, CA (US);
Charles Greef, Boulder, CO (US);
Daguang Wang, Vista, CA (US);
Nanogen Recognomics GmbH, Frankfurt am Main, DE;
Abstract
Methods of binding biomolecules to a substrate are provided that include contacting the biomolecule with a branched linking moiety to form a branched linking structure. The branched linking structure is then contacted with a binding moiety on the substrate to form a coupled substrate binding structure, thereby binding the biomolecule to the substrate. The biomolecule may contain a Lewis base or a nucleophile to react with a Lewis acid or electrophile in the branched linking moiety. Alternatively, the biomolecule may contain a Lewis acid or electrophile that can react with a Lewis base or nucleophile in the branched linking moiety. Additionally, the biomolecule can be bound to the substrate through a covalent or non-covalent bond.