The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2010

Filed:

May. 19, 2005
Applicants:

Markus M. Enzelberger, Planegg, DE;

Carl L. Hansen, Pasadena, CA (US);

Jian Liu, Pasadena, CA (US);

Stephen R. Quake, San Marino, CA (US);

Chiem MA, Pasadena, CA (US);

Inventors:

Markus M. Enzelberger, Planegg, DE;

Carl L. Hansen, Pasadena, CA (US);

Jian Liu, Pasadena, CA (US);

Stephen R. Quake, San Marino, CA (US);

Chiem Ma, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); F16K 11/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides microfluidic devices and methods using the same in various types of thermal cycling reactions. Certaom devices include a rotary microfluidic channel and a plurality of temperature regions at different locations along the rotary microfluidic channel at which temperature is regulated. Solution can be repeatedly passed through the temperature regions such that the solution is exposed to different temperatures. Other microfluidic devices include an array of reaction chambers formed by intersecting vertical and horizontal flow channels, with the ability to regulate temperature at the reaction chambers. The microfluidic devices can be used to conduct a number of different analyses, including various primer extension reactions and nucleic acid amplification reactions.


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