The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2010

Filed:

Oct. 27, 2006
Applicants:

Gary L. Griffiths, North Potomac, MD (US);

Serengulam V. Govindan, Summit, NJ (US);

Hans J. Hansen, Picayune, MS (US);

Inventors:

Gary L. Griffiths, North Potomac, MD (US);

Serengulam V. Govindan, Summit, NJ (US);

Hans J. Hansen, Picayune, MS (US);

Assignee:

Immunomedics, Inc., Morris Plains, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12P 21/04 (2006.01); C12P 21/08 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Embodiments of the invention relate to a method for treating target cells, tissues or pathogens in a subject, comprising administering a non-covalently bound complex which comprises a multispecific targeting protein and a hapten-enzyme covalent conjugate, followed by administration of a prodrug that is converted to an active drug by the enzyme. Other embodiments of the invention further relate to kits comprising the non-covalently bound complex or the components to prepare the complex.


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