The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2010
Filed:
Jul. 15, 2009
Lance G. Laing, Belmont, MA (US);
Timothy F. Smith, Dracut, MA (US);
John Gerstenmeier, Iii, Cleveland Heights, OH (US);
Gangadhar Jogikalmath, Cambridge, MA (US);
Lance G. Laing, Belmont, MA (US);
Timothy F. Smith, Dracut, MA (US);
John Gerstenmeier, III, Cleveland Heights, OH (US);
Gangadhar Jogikalmath, Cambridge, MA (US);
SRU Biosystems, Inc., Woburn, MA (US);
Abstract
A method of making a measurement of binding affinity of a sample comprises the steps of: introducing the sample into a well having a bottom formed as a photonic crystal biosensor, wherein a portion of the sample becomes bound to the biosensor; making a measurement of the change in the shift in peak wavelength value as a function of time (k) from the well as the sample is introduced into the well; simultaneously dispensing the sample to the well and aspirating the sample from the well and measuring the change in the shift in peak wavelength value as a function of time (k) during the simultaneous dispensing and aspirating, and calculating an equilibrium association constant or an equilibrium dissociation constant for the sample from the values of kand k.