The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Apr. 07, 2008
Applicants:
Matthew B. Seefeldt, Boulder, CO (US);
Lyndal K. Hesterberg, Boulder, CO (US);
Theodore W. Randolph, Niwot, CO (US);
John F. Carpenter, Littleton, CO (US);
Inventors:
Matthew B. Seefeldt, Boulder, CO (US);
Lyndal K. Hesterberg, Boulder, CO (US);
Theodore W. Randolph, Niwot, CO (US);
John F. Carpenter, Littleton, CO (US);
Assignee:
Barofold Inc., Aurora, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C12N 9/48 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Described herein are methods for the solubilization and proteolytic cleavage of fusion protein aggregates, including autocatalytic fusion proteins, at pressures greater than atmospheric pressure to yield soluble target polypeptides.