The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Jan. 16, 2009
Applicant:
Alfonso Bellacosa, Philadelphia, PA (US);
Inventor:
Alfonso Bellacosa, Philadelphia, PA (US);
Assignee:
Fox Chase Cancer Center, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); G01N 33/00 (2006.01); G01N 33/53 (2006.01); G01N 33/573 (2006.01); A01N 37/18 (2006.01); A01N 61/00 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61K 38/16 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or cancer screening assays. MED1, which recognizes and cleaves DNA, may also be used for the diagnostic detection of mutations and genetic variants.