The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 2010

Filed:

Sep. 16, 2005
Applicants:

Mehrdad Shamloo, San Jose, CA (US);

Donna Oksenberg, Palo Alto, CA (US);

Roman Urfer, Belmont, CA (US);

Inventors:

Mehrdad Shamloo, San Jose, CA (US);

Donna Oksenberg, Palo Alto, CA (US);

Roman Urfer, Belmont, CA (US);

Assignee:

M's Science Corporation, Minatojima-minamimachi, Chuo-ku, Kobe, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/50 (2006.01); A01N 43/60 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention discloses methods and compositions useful for facilitating neuronal regeneration and functional recovery in neurodegenerative diseases. The methods and compositions utilize ligands for the sigma receptor, wherein the ligand is preferably AGY-94806, or salts, or solvates thereof. These molecules can be delivered alone or in combination with agents which treat or prevent neurodegenerative diseases such as those caused by multiple sclerosis. In other methods, the sigma receptor ligands are administered after MS to facilitate functional recovery. The administration of the sigma receptor ligands causes faster functional recovery.


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