The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 2010

Filed:

Jan. 06, 2005
Applicants:

Ernst V. Arnold, Hagerstown, MD (US);

Blaine G. Doletski, Elkridge, MD (US);

Robert E. Raulli, Manassas, VA (US);

Inventors:

Ernst V. Arnold, Hagerstown, MD (US);

Blaine G. Doletski, Elkridge, MD (US);

Robert E. Raulli, Manassas, VA (US);

Assignee:

Amulet Pharmaceuticals, Inc., Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.


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