The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Sep. 09, 2005
Wanpen Tachaboonyakiat, Bangkok, TH;
Masakazu Kato, Aichi, JP;
Tooru Ooya, Ishikawa, JP;
Nobuhiko Yui, Ishikawa, JP;
Wanpen Tachaboonyakiat, Bangkok, TH;
Masakazu Kato, Aichi, JP;
Tooru Ooya, Ishikawa, JP;
Nobuhiko Yui, Ishikawa, JP;
Japan Science And Technology Agency, Kawaguchi-shi, JP;
Japan Tissue Engineering Co., Ltd., Gamagori-shi, JP;
Japan Advanced Institute of Science And Technology, Nomi-shi, JP;
Abstract
A cell-sheet releasing agent of the present invention contains an aminated polyrotaxane. The polyrotaxane constituting the skeleton of the cell-releasing agent of the present invention has a structure in which cavities of a plurality of cyclic molecules are threaded onto a linear molecule and both terminals of the linear molecule have a bulky cap bonded thereto so that the cyclic molecules are not dethreaded from the linear molecule. Furthermore, the aminated polyrotaxane contained in the cell-releasing agent of the present invention is a compound in which at least some of hydroxy groups in the cyclodextrin structure contained in the polyrotaxane are each substituted with a substituent having an amino group. According to this cell-sheet releasing agent, cultured cells anchored to the surface of a container can be released without damaging the cells and without controlling the temperature.