The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Dec. 27, 2005
Masanao Matsuo, Naka-gun, JP;
Hiroyuki Ebinuma, Ryugasaki, JP;
Osamu Miyazaki, Naka-gun, JP;
Kyoko Tanaka, Naka-gun, JP;
Akiko Suzuki, Ryugasaki, JP;
Masanao Matsuo, Naka-gun, JP;
Hiroyuki Ebinuma, Ryugasaki, JP;
Osamu Miyazaki, Naka-gun, JP;
Kyoko Tanaka, Naka-gun, JP;
Akiko Suzuki, Ryugasaki, JP;
Daiichi Pure Chemicals Co., Ltd., Tokyo, JP;
Abstract
The present invention is directed to a monoclonal antibody against a soluble fibrin, which specifically recognizes a conformation-changed site newly occurred in a C-terminal region of an Aα-chain of the soluble fibrin formed through thrombin digestion of fibrinogen. The present invention is also directed to a hybridoma which produces the antibody, an immunological assay method employing the antibody, and a method for evaluating hypercoagulability in a test sample by measuring the soluble fibrin level in the sample with the assay method. Through employment of the monoclonal antibody of the present invention, soluble fibrin on which plasmin has not acted, which reflects exclusively initial hypercoagulability, can be specifically detected.