The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
May. 11, 2009
Linda Masat, Walnut Creek, CA (US);
Mary Haak-frendscho, Newark, CA (US);
Arnold H. Horwitz, San Leandro, CA (US);
Gang Chen, San Diego, CA (US);
Marina Roell, Concord, CA (US);
Linda Masat, Walnut Creek, CA (US);
Mary Haak-Frendscho, Newark, CA (US);
Arnold H. Horwitz, San Leandro, CA (US);
Gang Chen, San Diego, CA (US);
Marina Roell, Concord, CA (US);
Xoma Technology Ltd., Berkeley, CA (US);
Abstract
Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO: 15 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.