The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2010
Filed:
Nov. 28, 2005
Timothy C. Gahman, Encinitas, CA (US);
Hengyuan Lang, San Diego, CA (US);
Mark R. Herbert, San Diego, CA (US);
Angelina M. Thayer, San Diego, CA (US);
Christian A. Hassig, Mira Mesa, CA (US);
Stewart A. Noble, San Diego, CA (US);
Russell D. Cousins, San Diego, CA (US);
Hui Zhuang, San Diego, CA (US);
Christopher R. Santos, Encinitas, CA (US);
Xiaohong Chen, San Diego, CA (US);
Timothy C. Gahman, Encinitas, CA (US);
Hengyuan Lang, San Diego, CA (US);
Mark R. Herbert, San Diego, CA (US);
Angelina M. Thayer, San Diego, CA (US);
Christian A. Hassig, Mira Mesa, CA (US);
Stewart A. Noble, San Diego, CA (US);
Russell D. Cousins, San Diego, CA (US);
Hui Zhuang, San Diego, CA (US);
Christopher R. Santos, Encinitas, CA (US);
Xiaohong Chen, San Diego, CA (US);
Kalypsys, Inc., San Diego, CA (US);
Abstract
The present invention relates to compounds and methods useful as inhibitors of nitric oxide synthase. Certain compounds of the subject invention have the following structural formula: wherein T, X, and Y are independently selected from the group consisting of CR, N, NR, S, and O; U is selected from the group consisting of CRand N; V is selected from the group consisting of CRand N; W and W' are independently selected from the group consisting of CH, CRR, NR, O, N(O), S(O)and C(O); n, m and p are independently an integer from 0 to 5; q is 0, 1, or 2; and other substituents are as defined herein. Other compounds of the subject invention have structural formulas as defined herein. Also disclosed herein are pharmaceutical compositions comprising the compounds of the subject invention.