The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7825222 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 02, 2010

Filed:

Dec. 08, 2005
Applicants:

Gregorio Aversa, Vancouver, CA;

Frank Kolbinger, Neuenburg, DE;

Josè M Carballido Herrera, Perchtoldsdorf, AT;

András Aszódi, Vienna, AT;

José W Saldanha, Enfield, GB;

Bruce M Hall, Strathfield, AU;

Inventors:

Gregorio Aversa, Vancouver, CA;

Frank Kolbinger, Neuenburg, DE;

Josè M Carballido Herrera, Perchtoldsdorf, AT;

András Aszódi, Vienna, AT;

José W Saldanha, Enfield, GB;

Bruce M Hall, Strathfield, AU;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

A molecule comprising at least one antigen binding site, comprising in sequence the hypervariable regions CDR1, CDR2 and CDR3, said CDR1 having the amino acid sequence Asn-Tyr-Ile-Ile-His (NYIIH), said CDR2 having the amino acid sequence Tyr-Phe-Asn-Pro-Tyr-Asn-His-Gly-Thr-Lys-Tyr-Asn-Glu-Lys-Phe-Lys-Gly (YFNPYNHGTKYNEKFKG) and said CDR3 having the amino acid sequence Ser-Gly-Pro-Tyr-Ala-Trp-Phe-Asp-Thr (SGPYAWFDT); e.g. further comprising in sequence the hypervariable regions CDR1', CDR2′ and CDR3′, CDR1′ having the amino acid sequence Arg-Ala-Ser-Gln-Asn-Ile-Gly-Thr-Ser-Ile-Gln (RASQNIGTSIQ), CDR2′ having the amino acid sequence Ser-Ser-Ser-Glu-Ser-Ile-Ser (SSSESIS) and CDR3′ having the amino acid sequence Gln-Gln-Ser-Asn-Thr-Trp-Pro-Phe-Thr (QQSNTWPFT), e.g. a chimeric or humanised antibody, useful as a pharmaceutical.


Find Patent Forward Citations

Aversa, Gregorio. (2010). Therapeutic binding molecules (U.S. Patent No. 7825222). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7825222

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