The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2010

Filed:

Mar. 08, 1996
Applicants:

Leif Christensen, Charlottenlund, DK;

Henrik Frydenlund Hansen, Radovre, DK;

Peter E. Nielsen, 2980 Kokkedal, DK;

Inventors:

Leif Christensen, Charlottenlund, DK;

Henrik Frydenlund Hansen, Radovre, DK;

Peter E. Nielsen, 2980 Kokkedal, DK;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 2/00 (2006.01); A61K 38/00 (2006.01); C07K 1/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/566 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods are provided for the nucleic acid mimic determination of nucleic acids. The compositions and methods may be used in the diagnosis and treatment of diseases amenable through modulation of nucleic acids which encode proteins that are implicated in disease states. In accordance with preferred embodiments, mimics are comprised of non-naturally occurring backbones to which are appended modified heterocyclic bases. Such bases preferably have sterically bulky substituents 1, 2, or 3 atoms removed from the sites of attachment to the backbone.


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