The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2010

Filed:

Oct. 21, 2005
Applicants:

Francis Wilson, Welwyn Garden City, GB;

Alison Reid, Cottenham, GB;

Valerie Reader, Linton, GB;

Richard John Harrison, Cambridge, GB;

Mihiro Sunose, Papisford, GB;

Remedios Hernandez-perni, Stalybridge, GB;

Jeremy Major, Cambridge, GB;

Cyrille Boussard, Saffron Walden, GB;

Kathryn Smelt, London, GB;

Jess Taylor, Hertfordshire, GB;

Adeline Leformal, Saffron Walden, GB;

Andrew Cansfield, Harston, GB;

Svenja Burckhardt, Boxworth, GB;

Inventors:

Francis Wilson, Welwyn Garden City, GB;

Alison Reid, Cottenham, GB;

Valerie Reader, Linton, GB;

Richard John Harrison, Cambridge, GB;

Mihiro Sunose, Papisford, GB;

Remedios Hernandez-Perni, Stalybridge, GB;

Jeremy Major, Cambridge, GB;

Cyrille Boussard, Saffron Walden, GB;

Kathryn Smelt, London, GB;

Jess Taylor, Hertfordshire, GB;

Adeline Leformal, Saffron Walden, GB;

Andrew Cansfield, Harston, GB;

Svenja Burckhardt, Boxworth, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/10 (2006.01); A61K 31/19 (2006.01); A01N 37/08 (2006.01); A01N 53/00 (2006.01); A61K 31/557 (2006.01); C07C 63/00 (2006.01); C07C 65/00 (2006.01); C07C 63/33 (2006.01); C07C 63/333 (2006.01); C07C 61/04 (2006.01); C07C 61/16 (2006.01); C07C 62/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds having the general formula (I) with the definitions of A, X, R-Rgiven below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of γ-secretase activity.


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