The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2010
Filed:
Aug. 30, 2004
Venkata P. Palle, Haryana, IN;
Sarala Balachandran, Delhi, IN;
Mohammad Salman, Haryana, IN;
Gagan Kukreja, Delhi, IN;
Nidhi Gupta, Delhi, IN;
Abhijit Ray, Delhi, IN;
Sunanda G. Dastidar, Delhi, IN;
Venkata P. Palle, Haryana, IN;
Sarala Balachandran, Delhi, IN;
Mohammad Salman, Haryana, IN;
Gagan Kukreja, Delhi, IN;
Nidhi Gupta, Delhi, IN;
Abhijit Ray, Delhi, IN;
Sunanda G. Dastidar, Delhi, IN;
Ranbaxy Laboratories Limited, New Delhi, IN;
Abstract
The present invention relates to isoxazoline derivatives, which can be used as selective inhibitors of phosphodiesterase (PDE) type IV. In particular, compounds disclosed herein can be useful in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive pulmonary disease (COPD), psoriasis, allergic rhinitis, shock, atopic dermatitis, Crohn's disease, adult respiratory distress syndrome (ARDS), eosinophilic granuloma, allergic conjunctivitis, osteoarthritis, ulcerative colitis and other inflammatory diseases in a patient, particularly in humans. The present invention also relates to processes for the preparation of disclosed compounds, as well as pharmaceutical compositions thereof, and their use as phosphodiesterase (PDE) type IV inhibitors.