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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7825126 B1

PDFFull Text
Expired
Date of Patent:
Nov. 02, 2010

Filed:

Sep. 02, 2005

Purine derivatives as a3 and a1 adenosine receptor agonists

Applicants:

Kenneth A. Jacobson, Silver Spring, MD (US);

Bhalchandra V. Joshi, Rockville, MD (US);

Susanna Tchilibon, Jerusalem, IL;

Inventors:

Kenneth A. Jacobson, Silver Spring, MD (US);

Bhalchandra V. Joshi, Rockville, MD (US);

Susanna Tchilibon, Jerusalem, IL;

Assignee:

The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);

Attorney:

Leydig, Voit & Mayer, Ltd.

Primary Examiner:

Mark L Berch

Int. Cl.
CPC ...
C07D 473/40 (2006.01); C07D 473/34 (2006.01); C07D 473/18 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61P 9/02 (2006.01); C07D 473/36 (2006.01); C07D 317/70 (2006.01); C07D 317/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are (N)-methanocarba adenine nucleosides of the formula: as highly potent Aadenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R-Rare as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both Aand Aadenosine receptors for use in cardioprotection.

Find Patent Forward Citations

Jacobson, Kenneth. (2010). Purine derivatives as a3 and a1 adenosine receptor agonists (U.S. Patent No. 7825126). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7825126

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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