The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2010
Filed:
Jun. 29, 2004
Applicant:
Philip N. Bryan, North Potomac, MD (US);
Inventor:
Philip N. Bryan, North Potomac, MD (US);
Assignee:
University of Maryland, College Park, College Park, MD (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/62 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12N 15/75 (2006.01); C12N 15/79 (2006.01); C12N 15/81 (2006.01); C12N 15/85 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is directed to the identification of a protease prodomain that is capable of binding a corresponding protease with high affinity. The protease prodomain of the present invention is fused to a second protein to form a protease prodomain fusion protein. The presence of a protease prodomain protein in a fusion protein allows for easy and selective purification of the second protein by incubation with the corresponding protease.