The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Aug. 23, 2007
Ben-zion Dolitzky, Petach Tiqva, IL;
Evgeny Shapiro, Haifa, IL;
Santiago Ini, Haifa, IL;
Yaron Shmuely, Hedera, IL;
Eli Lancry, Modiin, IL;
Ben-Zion Dolitzky, Petach Tiqva, IL;
Evgeny Shapiro, Haifa, IL;
Santiago Ini, Haifa, IL;
Yaron Shmuely, Hedera, IL;
Eli Lancry, Modiin, IL;
Teva Pharmaceutical Industries Ltd., Petah Tiqva, IL;
Abstract
The present invention provides 3-benzyloxy-2-aminopyridine (BOPA), 3-(2-Hydroxyethyl)-2-methyl-9-hydoxy-4H-pyrido[1,2-a]pyrimidine-4-one (HMBP), 3-(2-Chloroethyl)-2-methyl-9-hydoxy-4H-pyrido[1,2-a]pyrimidine-4-one (CMHP) and 3-(2-chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrrido[1,2-a]-pyrimidin-4-one (CMHTP) useful as intermediates for the preparation of paliperidone. The present invention also provides processes for preparing these intermediates and for preparing paliperidone.