The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Jan. 30, 2009
Kazuhisa Shimizu, Maebashi, JP;
Toshitaka Murata, Kita-ku, JP;
Katsuhiko Sagawa, Namerikawa, JP;
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Nanocarrier Kabushiki Kaisha, Chiba, JP;
Abstract
A novel micellar preparation in which the solubility of a sparingly water-soluble anticancer agent has been heightened and which after intravenous administration, enables a high blood concentration to be maintained. The preparation has high medicinal activity and/or is reduced in side effects. The micellar preparation is formed from a block copolymer represented by the following general formula (1): [wherein R1 represents hydrogen or Calkyl; R2 represents Calkylene; R3 represents methylene or ethylene; R4 represents hydrogen or Cacyl; R5 represents hydroxyl, optionally substituted aryl Calkoxyl, substituted Calkylamino, or amino having a residue of either an amino acid or a peptide derivative; n is an integer of 5 to 1,000; m is an integer of 2 to 300; and x is an integer of 1 to 300; provided that the proportion of hydroxy in the R5's is 0 to 99% and x is not larger than m] and a sparingly water-soluble anticancer agent.