The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2010

Filed:

Apr. 20, 2005
Applicants:

Adnan M. M. Mjalli, Jamestown, NC (US);

Bapu R. Gaddam, Greensboro, NC (US);

Ghassan Qabaja, High Point, NC (US);

Govindan Subramanian, High Point, NC (US);

Jeff Zhu, Greensboro, NC (US);

John Dankwardt, Westborough, MA (US);

Murty N. Arimilli, Oak Ridge, NC (US);

Robert C. Andrews, Jamestown, NC (US);

Samuel Victory, Oak Ridge, NC (US);

YE E. Tian, Jamestown, NC (US);

Inventors:

Adnan M. M. Mjalli, Jamestown, NC (US);

Bapu R. Gaddam, Greensboro, NC (US);

Ghassan Qabaja, High Point, NC (US);

Govindan Subramanian, High Point, NC (US);

Jeff Zhu, Greensboro, NC (US);

John Dankwardt, Westborough, MA (US);

Murty N. Arimilli, Oak Ridge, NC (US);

Robert C. Andrews, Jamestown, NC (US);

Samuel Victory, Oak Ridge, NC (US);

Ye E. Tian, Jamestown, NC (US);

Assignee:

TransTech Pharma, Inc., High Point, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61K 31/381 (2006.01); C07D 277/38 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides substituted heteroaryl derivatives of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and methods of use in treating human or animal disorders. The compounds of the invention can be useful as inhibitors of action of AgRP on a melanocortin receptor and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases which may be responsive to the modulation of melanocortin receptors including obesity-related disorders.


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