The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Feb. 22, 2006
Kazuo Hattori, Kamakura, JP;
Satoshi Niizuma, Kamakura, JP;
Miyako Masubuchi, Kamakura, JP;
Kohei Koyama, Kamakura, JP;
Osamu Kondoh, Kamakura, JP;
Toshiyuki Tsukaguchi, Kamakura, JP;
Takehiro Okada, Kamakura, JP;
Kazuo Hattori, Kamakura, JP;
Satoshi Niizuma, Kamakura, JP;
Miyako Masubuchi, Kamakura, JP;
Kohei Koyama, Kamakura, JP;
Osamu Kondoh, Kamakura, JP;
Toshiyuki Tsukaguchi, Kamakura, JP;
Takehiro Okada, Kamakura, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
The present invention provides a compound having high antitumor activity, which is useful for therapeutic and preventive agents effective for proliferative diseases such as cancer; a production method thereof; an intermediate compound useful for such production; and a pharmaceutical composition comprising such a compound. The present invention provides a compound represented by the formula (1): wherein X represents an aryl group or heteroaryl group which may be substituted, Cy represents a 4- to 7-membered monocyclic heterocyclic ring or a 8- to 10-membered condensed heterocyclic ring which may be substituted, and Z represents O, S, or NRa; or a prodrug thereof; or a pharmaceutically acceptable salt thereof; and a pharmaceutical and a pharmaceutical composition which comprise the compound.