The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2010

Filed:

Oct. 03, 2008
Applicants:

Lee D. Arnold, Mt. Sinai, NY (US);

Cara Cesario, Mishawaka, IN (US);

Heather Coate, Farmingdale, NY (US);

Andrew Philip Crew, North Babylon, NY (US);

Hanqing Dong, Syosset, NY (US);

Kenneth Foreman, Syosset, NY (US);

Ayako Honda, Quincy, MA (US);

Radoslaw Laufer, Ontario, CA;

An-hu LI, Commack, NY (US);

Kristen Michelle Mulvihill, E. Northport, NY (US);

Mark J. Mulvihill, E. Northport, NY (US);

Anthony I. Nigro, Westwood, NJ (US);

Bijoy Panicker, Holtsville, NY (US);

Arno G. Steinig, E. Northport, NY (US);

Yingchuan Sun, Waltham, MA (US);

Quinghua Weng, West Islip, NY (US);

Douglas S. Werner, Holtsville, NY (US);

Michael J. Wyle, Rockville Centre, NY (US);

Tao Zhang, Waltham, MA (US);

Inventors:

Lee D. Arnold, Mt. Sinai, NY (US);

Cara Cesario, Mishawaka, IN (US);

Heather Coate, Farmingdale, NY (US);

Andrew Philip Crew, North Babylon, NY (US);

Hanqing Dong, Syosset, NY (US);

Kenneth Foreman, Syosset, NY (US);

Ayako Honda, Quincy, MA (US);

Radoslaw Laufer, Ontario, CA;

An-Hu Li, Commack, NY (US);

Kristen Michelle Mulvihill, E. Northport, NY (US);

Mark J. Mulvihill, E. Northport, NY (US);

Anthony I. Nigro, Westwood, NJ (US);

Bijoy Panicker, Holtsville, NY (US);

Arno G. Steinig, E. Northport, NY (US);

Yingchuan Sun, Waltham, MA (US);

Quinghua Weng, West Islip, NY (US);

Douglas S. Werner, Holtsville, NY (US);

Michael J. Wyle, Rockville Centre, NY (US);

Tao Zhang, Waltham, MA (US);

Assignee:

OSI Pharmaceuticals, Inc., Ardsley, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2006.01); A01N 43/64 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X, X, X, X, X, X, X, R, and Qare defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.


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