The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Dec. 20, 2006
Samit Kumar Bhattacharya, Groton, CT (US);
Michael Joseph Luzzio, Noank, CT (US);
Donn Gregory Wishka, Mystic, CT (US);
Gonghua Pan, Old Lyme, CT (US);
Arthur Douglas Brosius, Niantic, CT (US);
Joel Thomas Arcari, Groton, CT (US);
James Alfred Southers, Jr., Norwich, CT (US);
Kendra Louise Nelson, New London, CT (US);
Jun Xiao, Waterford, CT (US);
Samit Kumar Bhattacharya, Groton, CT (US);
Michael Joseph Luzzio, Noank, CT (US);
Donn Gregory Wishka, Mystic, CT (US);
Gonghua Pan, Old Lyme, CT (US);
Arthur Douglas Brosius, Niantic, CT (US);
Joel Thomas Arcari, Groton, CT (US);
James Alfred Southers, Jr., Norwich, CT (US);
Kendra Louise Nelson, New London, CT (US);
Jun Xiao, Waterford, CT (US);
Pfizer Inc, New York, NY (US);
Pfizer Products Inc, New York, NY (US);
Abstract
The present invention relates to a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formula and R, R, R, A, K, M, L, L, X, Y, Y, Q, salt thereof, wherein R, R, R, A, K, L, L, W, X, Z, Z, Y, Y, Z, Z, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.