The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Nov. 21, 2005
Helle Krogh Ottow, Mårslet, DK;
Mette Munch, Egå, DK;
Thor Las Holtet, Rønde, DK;
Mikkel Holmen Andersen, Sporup, DK;
Josephus Dirk Nieland, Aarhus C, DK;
Helle Krogh Ottow, Mårslet, DK;
Mette Munch, Egå, DK;
Thor Las Holtet, Rønde, DK;
Mikkel Holmen Andersen, Sporup, DK;
Josephus Dirk Nieland, Aarhus C, DK;
Anaphore, Inc., La Jolla, CA (US);
Abstract
TNF binding polypeptides based on human tetranectin C-type lectin like domains (CTLD) with improved binding characteristics and improved efficacy. The polypeptides comprise a TNF binding domain having the amino acid sequence KRWS-RYF (SEQ ID NO:1). Also provided are methods of preparing the polypeptides of the invention. The polypeptides may be used for the preparation of pharmaceutical compositions, and for treatment of a subject having a pathology mediated by TNF, such as treatment of rheumatoid arthritis.