The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Nov. 06, 2006
Godelieve Irma Christine Maria Heylen, Westmalle, BE;
Cornelus Gerardus Maria Janssen, Vosselaar, BE;
Mirek Jurzak, Frankfurt am Main, DE;
Henricus Petrus Martinus Maria Van Assouw, Oirschot, NL;
Godelieve Irma Christine Maria Heylen, Westmalle, BE;
Cornelus Gerardus Maria Janssen, Vosselaar, BE;
Mirek Jurzak, Frankfurt am Main, DE;
Henricus Petrus Martinus Maria Van Assouw, Oirschot, NL;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention provides assays and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. Said assays and kits are based on the finding that the interaction of astemizole with the HERG potassium channel can be exploited to predict cardiotoxicity of compounds during the development of new therapeutics and other agents.