The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
Nov. 10, 2004
Svend K. Petersen-mahrt, Cambridge, GB;
Reuben Harris, Cambridge, GB;
Michael Samuel Neuberger, Cambridge, GB;
Rupert Christopher Landsdowne Beale, Cambridge, GB;
Svend K. Petersen-Mahrt, Cambridge, GB;
Reuben Harris, Cambridge, GB;
Michael Samuel Neuberger, Cambridge, GB;
Rupert Christopher Landsdowne Beale, Cambridge, GB;
Medical Research Council, London, GB;
Abstract
The present invention identifies that the expression of Activation Induced Deaminase (AID) or its homologues in cells confers a mutator phenotype and thus provides a method for generating diversity in a gene or gene product as well as cell lines capable of generating diversity in defined gene products. The invention also provides methods of modulating a mutator phenotype by modulating AID expression or activity.