The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 2010
Filed:
May. 07, 2007
Applicants:
Ronald Vogels, Linschoten, NL;
Abraham Bout, Moerkapelle, NL;
Inventors:
Ronald Vogels, Linschoten, NL;
Abraham Bout, Moerkapelle, NL;
Assignee:
Crucell Holland B.V., Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); C12N 15/00 (2006.01); C12N 15/34 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to methods and means for producing adenoviral vectors on complementing cell lines, wherein the early region 4 open reading frame 6 (E4-orf6) encoding nucleic acid is present in the adenoviral vector and wherein the E4-orf6 gene product is compatible with one or more products of the E1 gene products provided by the complementing cell, such that the adenoviral vector can be efficiently produced by the complementing cell.