The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 2010

Filed:

Jul. 22, 2005
Applicants:

Shuang-yong Xu, Lexington, MA (US);

Zhenyu Zhu, Beverly, MA (US);

Timothy Meixsell, Topsfield, MA (US);

Inventors:

Shuang-Yong Xu, Lexington, MA (US);

Zhenyu Zhu, Beverly, MA (US);

Timothy Meixsell, Topsfield, MA (US);

Assignee:

New England Biolabs, Inc., Ipswich, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); C07K 14/00 (2006.01); C12P 21/00 (2006.01); C12N 15/00 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/44 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A nicking endonuclease is described which has an amino acid sequence with at least 70% identity to SEQ ID NO:6 and comprising a mutation at least one of an arginine or glutamic acid corresponding to position 507 and position 546 respectively in SEQ ID NO:6.


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