The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 2010

Filed:

Oct. 06, 2006
Applicants:

Junji Sato, Tokyo, JP;

Kazuyuki Hattori, Tokyo, JP;

Hirokazu Kubota, Tokyo, JP;

Ryosuke Munakata, Tokyo, JP;

Toru Asano, Tokyo, JP;

Junko Maeda, Tokyo, JP;

Masakatsu Kawakami, Tokyo, JP;

Akio Kamikawa, Tokyo, JP;

Inventors:

Junji Sato, Tokyo, JP;

Kazuyuki Hattori, Tokyo, JP;

Hirokazu Kubota, Tokyo, JP;

Ryosuke Munakata, Tokyo, JP;

Toru Asano, Tokyo, JP;

Junko Maeda, Tokyo, JP;

Masakatsu Kawakami, Tokyo, JP;

Akio Kamikawa, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 63/33 (2006.01); C07C 321/00 (2006.01); C07D 277/04 (2006.01); C07D 333/62 (2006.01); C07D 231/10 (2006.01); C07D 211/78 (2006.01); A01N 43/40 (2006.01); A01N 43/82 (2006.01); A01N 43/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general formula (I): wherein A is an optionally substituted aryl or heteroaryl, and B is an optionally substituted monocyclic heteroaryl; and a pharmaceutical composition comprising the same and a pharmaceutically acceptable carrier. The triarylcarboxylic acid derivative (I) exhibits potent xanthine oxidase inhibiting action and is therefore useful as a therapeutic agent for preventing or treating hyperuricemia, gout, inflammatory bowel disease, diabetic nephropathy and diabetic retinopathy.


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