The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Nov. 24, 2008
Applicants:
Herve Bouchard, Thiais, FR;
Alain Commercon, Vitry-sur-Seine, FR;
Ravi V. J. Chari, Newton, MA (US);
Inventors:
Herve Bouchard, Thiais, FR;
Alain Commercon, Vitry-sur-Seine, FR;
Ravi V. J. Chari, Newton, MA (US);
Assignee:
Sanofi-Aventis, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 309/30 (2006.01);
U.S. Cl.
CPC ...
Abstract
Leptomycin derivatives having a moiety, such as a sulfide or a disulfide, that can conjugate to a cell binding reagent such as an antibody are disclosed. The therapeutic use of such leptomycin derivative conjugates is also described; such conjugates have therapeutic use because they can deliver cytotoxic leptomycin derivatives to a specific cell population in a targeted fashion.