The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Jul. 16, 2003
Kayoko Kawashima, Takatsuki, JP;
Naruto Katsuragi, Ibaraki, JP;
Keijiro Sugimura, Ibaraki, JP;
Mayumi Furuya, Osaka, JP;
Ryuichi Morishita, Osaka, JP;
Kayoko Kawashima, Takatsuki, JP;
Naruto Katsuragi, Ibaraki, JP;
Keijiro Sugimura, Ibaraki, JP;
Mayumi Furuya, Osaka, JP;
Ryuichi Morishita, Osaka, JP;
Asubio Pharma Co., Ltd., Tokyo, JP;
Abstract
The present invention provides methods for screening drugs inhibiting the expression of OSF-2 gene or the production or function of the protein encoded thereby and therapeutic agents for heart failure having such effects. Useful methods for diagnosing heart failure can be provided by monitoring the expression or variation of said gene or the production of the protein encoded thereby. The present invention also provides transgenic animals with forced expression of OSF-2 gene and methods for studying changes in gene expression or protein production or the functions of various genes or proteins with the progress of the pathology of heart failure using them and novel therapeutic agents for heart failure.