The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7816369 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 19, 2010

Filed:

Nov. 03, 2005
Applicants:

Oivin M. Guicherit, San Diego, CA (US);

Edward Andrew Boyd, Henfield, GB;

Judith Boyd, Legal Representative, Henfield, GB;

Shirley Ann Brunton, Berkshire, GB;

Stephen Price, Hertford, GB;

John Harry Alexander Stibbard, Oxfordshire, GB;

Colin H. Mackinnon, Oxfordshire, GB;

Inventors:

Oivin M. Guicherit, San Diego, CA (US);

Edward Andrew Boyd, Henfield, GB;

Judith Boyd, legal representative, Henfield, GB;

Shirley Ann Brunton, Berkshire, GB;

Stephen Price, Hertford, GB;

John Harry Alexander Stibbard, Oxfordshire, GB;

Colin H. MacKinnon, Oxfordshire, GB;

Assignees:

Curis, Inc., Cambridge, MA (US);

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4427 (2006.01); C07D 471/04 (2006.01); C07D 413/02 (2006.01); C07D 401/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.


Find Patent Forward Citations

Guicherit, Oivin. (2010). Mediators of hedgehog signaling pathways, compositions and uses related thereto (U.S. Patent No. 7816369). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7816369

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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