The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Dec. 22, 2008
Lieven Meerpoel, Beerse, BE;
Leo Jacobus Jozef Backx, Arendonk, BE;
Libuse Jaroskova, Vosselaar, BE;
Peter Walter Maria Roevens, Malle, BE;
Louis Jozef Elisabeth Van Der Veken, Vosselaar, BE;
Marcel Viellevoye, Breda, NL;
Joannes Theodorus Maria Linders, Eindhoven, NL;
Lieven Meerpoel, Beerse, BE;
Leo Jacobus Jozef Backx, Arendonk, BE;
Libuse Jaroskova, Vosselaar, BE;
Peter Walter Maria Roevens, Malle, BE;
Louis Jozef Elisabeth Van Der Veken, Vosselaar, BE;
Marcel Viellevoye, Breda, NL;
Joannes Theodorus Maria Linders, Eindhoven, NL;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention is concerned with novel aryl piperidine or piperazine compounds substituted with certain 5-membered heterocycles having apoB secretion/MTP inhibiting activity and concomitant lipid lowering activity. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of hyperlipidemia, obesity and type II diabetes. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use of said compounds as a medicine for the treatment of atherosclerosis, pancreatitis, obesity, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, diabetes and type II diabetes.