The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 2010

Filed:

Feb. 04, 2005
Applicants:

Kveta Fuksova, Praha, CZ;

Libor Havlicek, Praha, CZ;

Vladimir Krystof, Ostrava, CZ;

Rene Lenobel, Frydek Mistek, CZ;

Miroslav Strnad, Olomouc, CZ;

Inventors:

Kveta Fuksova, Praha, CZ;

Libor Havlicek, Praha, CZ;

Vladimir Krystof, Ostrava, CZ;

Rene Lenobel, Frydek Mistek, CZ;

Miroslav Strnad, Olomouc, CZ;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 25/28 (2006.01); A61P 17/06 (2006.01); A61P 3/10 (2006.01); A61P 13/12 (2006.01); A61P 37/02 (2006.01); A61P 31/20 (2006.01); A61P 31/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a compound of formula I, or a pharmaceutically acceptable acid salt thereof. The invention further relates to the use of such compounds in the treatment of hyperproliferative skin disorders, viral infections, cancer, rheumatoid arthritis, lupus, type I diabetes, multiple sclerosis, restenosis, polycystic kidney disease, graft rejection, graft versus host disease and gout, or for psoriasis, parasitoses such as those caused by fungi or protists, or Alzheimer's disease. Further aspects of the invention relate to the use of such compounds in the inhibition of cell proliferation, in the induction of apoptosis, to modulate the activity of adrenergic and/or purinergic receptors or to suppress immunostimulation. The invention also relates to the use of 2,6,9-trisubstituted 8-azapurines in maintaining mammalian ooctyes at the germinal vesicle stage.


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