The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Jun. 29, 2006
Kerstin Kühn-wache, Halle/Saale, DE;
Joachim Bär, Halle/Saale, DE;
Hans-ulrich Demuth, Halle/Saale, DE;
Torsten Hoffmann, Halle/Saale, DE;
Ulrich Heiser, Halle/Saale, DE;
Wolfgang Brandt, Halle/Saale, DE;
Kerstin Kühn-Wache, Halle/Saale, DE;
Joachim Bär, Halle/Saale, DE;
Hans-Ulrich Demuth, Halle/Saale, DE;
Torsten Hoffmann, Halle/Saale, DE;
Ulrich Heiser, Halle/Saale, DE;
Wolfgang Brandt, Halle/Saale, DE;
OSI Pharmaceuticals, Inc., Ardsley, NY (US);
Abstract
The present application relates to the secondary binding site of dipeptidyl peptidase IV, its relationship amongst substrates and to the modulation of substrate specificity of dipeptidyl peptidase IV (DP IV, synonym: DPP IV, CD26, EC 3.4.14.5). The application relates further to compounds that bind to the secondary binding site of DP IV and their use to modulate the substrate specificity of DP IV; methods of treatment of various DP IV mediated disorders; and screening methods for the identification of secondary binding sites on DP IV and DP IV-like enzymes.