The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Feb. 22, 2008
Justin R. Fallon, Brooklyn, CT (US);
Mark A. Bowe, Damascus, MD (US);
Beth Mckechnie, Franklin, MA (US);
Michael Rafii, San Diego, CA (US);
Alison Amenta, Pawtucket, RI (US);
Mary Lynn Mercado, Robbinsville, NJ (US);
Hiroki Hagiwara, Tokyo, JP;
Justin R. Fallon, Brooklyn, CT (US);
Mark A. Bowe, Damascus, MD (US);
Beth McKechnie, Franklin, MA (US);
Michael Rafii, San Diego, CA (US);
Alison Amenta, Pawtucket, RI (US);
Mary Lynn Mercado, Robbinsville, NJ (US);
Hiroki Hagiwara, Tokyo, JP;
Brown University Research Foundation, Providence, RI (US);
Abstract
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.