The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2010
Filed:
Apr. 01, 2005
Mien-chie Hung, Houston, TX (US);
Chi-ping Day, Houston, TX (US);
Kun-ming Rau, Niau-Sung Shiang, TW;
Xiaoming Xie, Houston, TX (US);
Zheng LI, Pearland, TX (US);
Mien-Chie Hung, Houston, TX (US);
Chi-Ping Day, Houston, TX (US);
Kun-Ming Rau, Niau-Sung Shiang, TW;
Xiaoming Xie, Houston, TX (US);
Zheng Li, Pearland, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase IIα and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile