The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2010

Filed:

Nov. 30, 2001
Applicants:

Anthony Treston, Rockville, MD (US);

Jamshed H. Shah, Columbia, MD (US);

Robert J. D'amato, Lexington, MA (US);

Kimberly A. Hunsucker, Alpharetta, GA (US);

John Rougas, Westchester, PA (US);

Barry P. Conner, Laurel, MD (US);

Victor Pribdula, Silver Spring, MD (US);

Glenn M. Swartz, Mt. Airy, MD (US);

Inventors:

Anthony Treston, Rockville, MD (US);

Jamshed H. Shah, Columbia, MD (US);

Robert J. D'Amato, Lexington, MA (US);

Kimberly A. Hunsucker, Alpharetta, GA (US);

John Rougas, Westchester, PA (US);

Barry P. Conner, Laurel, MD (US);

Victor Pribdula, Silver Spring, MD (US);

Glenn M. Swartz, Mt. Airy, MD (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides new and useful analogs of 4-amino-thalidomide. These analogs include S(−)-4-amino-thalidomide and R(+)-4-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.


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