The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 2010
Filed:
Oct. 11, 2004
Manuel Ferrer, Madrid, ES;
Kenneth Timmis, Wolfenbüttel, DE;
Tatjana Chernikova, Tashkent, UZ;
Peter Golyshin, Wolfenbüttel, DE;
Michail Yakimov, Messina, IT;
Manuel Ferrer, Madrid, ES;
Kenneth Timmis, Wolfenbüttel, DE;
Tatjana Chernikova, Tashkent, UZ;
Peter Golyshin, Wolfenbüttel, DE;
Michail Yakimov, Messina, IT;
Helmholtz-Zentrum für Infektionsforschung GmbH, Braunschweig, DE;
Abstract
The invention relates to the growth temperature of organisms, especially plants and microorganisms and the manipulation of the tolerable cultivation temperature. More specifically, the present invention relates to the expression of heterologous proteins in microorganisms, and especially to the heterologous expression of heat sensitive proteins in bacteria, either gram-negative or gram-positive. In a first aspect, the present invention provides a method for manipulation of cells and the resultant cells, wherein at least one gene from a psychrophilic micro organism coding for at least one chaperone or chaperonin is expressed. Such cells are selected among cultivated eukaryotic cells, i.e. animal and plant cells and entire plants, gram-negative and gram-positive bacteria, fungi and yeasts.