The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 2010
Filed:
Jun. 28, 2004
Peter A. Seubert, South San Francisco, CA (US);
Carmen Vigo-pelfrey, Mountain View, CA (US);
Dale B. Schenk, Pacifica, CA (US);
Robin Barbour, Newark, CA (US);
Peter A. Seubert, South San Francisco, CA (US);
Carmen Vigo-Pelfrey, Mountain View, CA (US);
Dale B. Schenk, Pacifica, CA (US);
Robin Barbour, Newark, CA (US);
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
This invention provides methods useful in aiding in the diagnosis of Alzheimer's disease. The methods involve measuring the amount of amyloid-β peptide (x−≧41) in the cerebrospinal fluid of a patient. High levels of the peptide generally are inconsistent with a diagnosis of Alzheimer's. Low levels of the peptide are consistent with the disease and, with other tests, can provide a positive diagnosis. Other methods involve measuring the amounts of both Aβ(x−≧41) and tau. Low levels of Aβ(x−≧41) and high levels of tau are a positive indicator of Alzheimer's disease, while high levels of Aβ(x−≧41) and low levels of tau are a negative indication of Alzheimer's disease.