The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 2010

Filed:

Mar. 28, 2007
Applicants:

Stephan Zuchner, Pinecrest, FL (US);

Margaret Pericak-vance, Coral Gables, FL (US);

Allison Ashley-koch, Cary, NC (US);

Corey Braastad, Southampton, MA (US);

Narasimhan Nagan, South Grafton, MA (US);

Hui Zhu, Belmont, MA (US);

Jeffrey G. Jones, Wilbraham, MA (US);

Inventors:

Stephan Zuchner, Pinecrest, FL (US);

Margaret Pericak-Vance, Coral Gables, FL (US);

Allison Ashley-Koch, Cary, NC (US);

Corey Braastad, Southampton, MA (US);

Narasimhan Nagan, South Grafton, MA (US);

Hui Zhu, Belmont, MA (US);

Jeffrey G. Jones, Wilbraham, MA (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of identifying polymorphisms associated with hereditary spastic paraplegia (SPG), are described. The polymorphisms associated with SPG include specific mutations in the receptor expression enhancing protein 1 (REEP1) gene. Also described are methods of diagnosis of SPG.


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