The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Mar. 17, 2006
Akihiro Ishii, Saitama, JP;
Takashi Ootsuka, Saitama, JP;
Manabu Yasumoto, Saitama, JP;
Hideyuki Tsuruta, Saitama, JP;
Kenjin Inomiya, Saitama, JP;
Koji Ueda, Saitama, JP;
Kaori Mogi, Saitama, JP;
Akihiro Ishii, Saitama, JP;
Takashi Ootsuka, Saitama, JP;
Manabu Yasumoto, Saitama, JP;
Hideyuki Tsuruta, Saitama, JP;
Kenjin Inomiya, Saitama, JP;
Koji Ueda, Saitama, JP;
Kaori Mogi, Saitama, JP;
Central Glass Company, Limited, Ube-shi, JP;
Abstract
It was found that a fluoro derivative can be produced by reacting a hydroxy derivative with sulfuryl fluoride (SOF) in the presence of an organic base or in the presence of an organic base and 'a salt or complex comprising an organic base and hydrogen fluoride'. According to the present production process, it is not necessary to use perfluoroalkanesulfonyl fluoride, which is not preferable in industrial use, and it is possible to advantageously produce optically-active fluoro derivatives, which are important intermediates of medicines, agricultural chemicals and optical materials, specifically 4-fluoroproline derivatives, 2'-deoxy-2′-fluorouridine derivatives, optically-active α-fluorocarboxylate derivatives, and the like, even in a large scale.