The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Jul. 27, 2004
Salvador Puig Torres, Barcelona, ES;
Reyes Herbera Espinal, Barcelona, ES;
Pere Dalmases Barjoan, Sant Feliu de Llobregat, ES;
Salvador Puig Torres, Barcelona, ES;
Reyes Herbera Espinal, Barcelona, ES;
Pere Dalmases Barjoan, Sant Feliu de Llobregat, ES;
Inke, S.A., Castellbisbal, ES;
Abstract
The invention relates to a procedure for preparing quetiapine by reaction between a compound of formula (II) and a compound of formula (III), in which X means a leaving group and P a protective group of alcohols resistant to alkaline conditions, in the presence of a base, followed by a step of deprotection and, optionally, obtaining a pharmaceutically acceptable salt thereof. Said procedure permits the obtaining of quetiapine with a high degree of purity under soft temperature conditions, with short reaction times and avoiding the use of toxic solvents. (Graphic)