The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 2010
Filed:
Jul. 23, 1998
Applicants:
Robert Bridenbaugh, Millbrae, CA (US);
Warren Dang, Alameda, CA (US);
Lee B. Bussey, San Mateo, CA (US);
Inventors:
Robert Bridenbaugh, Millbrae, CA (US);
Warren Dang, Alameda, CA (US);
Lee B. Bussey, San Mateo, CA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/06 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods are provided for producing highly purified compositions of nucleic acids by using a highly streamlined and readily automated process. The methods use static mixers for lysing cells and precipitating debris, followed by centrifugation and ion exchange chromatography. The process may include a purification step using tangential flow ultrafiltration. A scaleable process for producing pharmaceutical grade plasmid DNA, useful for gene therapy, is provided.